LCGC: 4 Part Series: Streamline Routine Volatiles Analysis - Filling the Awkward Gap Between GC and LC
Direct mass spectrometry (direct MS) facilitates faster method development and validation, plus it provides high throughput for routine analysis. But the benefit of adoption of selected ion flow tube mass spectrometry (SIFT-MS)—the leading automated direct mass spectrometry technique for analysis of volatile compounds—also has an additional benefit: greatly simplifying the analysis of important chromatographically challenging volatiles, such as formaldehyde, volatile fatty acids, organosulfur compounds (and hydrogen sulfide), and amines (and ammonia). Straightforward analysis without requiring derivatization, drying steps, or selection of special columns, detectors, or analysis conditions is a direct result of the soft chemical ionization used in SIFT-MS.
This final webcast (of a series of four) on routine SIFT-MS analysis focuses on case studies that demonstrate simple analysis of chromatographically volatile compounds. Formaldehyde receives special attention as it is of important across a wide range of industries (from environmental to pharmaceutical testing) and its case study also includes validation of an unconventional analytical method in compliance with ICH Q2(R1) Guidelines for regulatory submission.
Presenter: Mark Perkins, PhD (Senior Applications Chemist, Anatune Limited, United Kingdom)
Mark is a senior applications chemist at Anatune Limited and a global authority in automated SIFT-MS. Mark has extensive experience in both conventional chromatographic methods as well as SIFT-MS. Prior to joining Anatune, he spent 12 years as a senior analyst and chromatography section manager at the Malaysian Rubber Board’s UK research center.
Presenter: Vaughan Langford, PhD (Principal Scientist, Syft Technologies, New Zealand)
Vaughan joined Syft in 2002 after completing his PhD in Physical Chemistry at the University of Canterbury, and post-doctoral fellowships at the Universities of Geneva, Western Australia, and Canterbury. With an extensive background in diverse applications of SIFT-MS, he provides advanced applications support to SIFT-MS users globally.