Dioxins are persistent organic pollutants (POPs) that have a stable structure and can remain in the environment persistently. In addition to being present in environmental samples, these pollutants can also enter the food chain. Thus, there is a need for monitoring these toxic compounds in both environmental and food samples. A variety of regulating guidance documents and methods, including EPA 1613, EPA1668, EPA 8290, EN-1948-1, EN-1948-2, JSA JIS K 0311:2005 provides guidance on separation of dioxins, furans and dioxin-like PCBs. Unfortunately, with the existing gas chromatography (GC) products at their disposal, scientists have experienced incredibly long method run times, with two columns and two GC–high-resolution mass spectrometry (GC–HRMS) instruments needed to confirm the coelutions. In addition, the traditional 5% phenyl phase doesn’t give adequate separation of critical tetra dioxins and furans.
In this webcast, we will explore newly developed GC stationary-phases that are specifically created for improved dioxin analyses. We will explore applications that demonstrates increased resolution of tetra dioxins and furans as a single column solution that lends to potential huge gains in productivity and method speed. We will explore optimal column dimensions that provides enhanced resolution and shorter run times. Additionally, column protection options will be explored to extend the column life time.
Presenter: Ramkumar Dhandapani, PhD (Global Product Manager Gas Chromatography, Phenomenex)
Dr. Ramkumar Dhandapani has been in the chromatography industry for over 15 years with hands-on and troubleshooting experience. He has earnt a master’s and PhD degree in Analytical chemistry from Seton Hall University with specialization in Microextractions, Multidimensional Gas Chromatography and Tandem Mass Specs techniques. He has developed and validated several regulatory compliant methods in Pharmaceutical, Food, Fuels and Environmental industry as well as incorporated method improvement and troubleshooting across a range of GC techniques. Dr. Dhandapani joined Phenomenex in August of 2014 and he serves as the Global Product Manager-Gas Chromatography at Phenomenex. In addition to managing the GC product line, Dr. Dhandapani presents on innovations in Gas Chromatography at various chromatography conference.
Presenter: Andrew Patterson (Technical Director, Eurofins Specialty Services)
Andrew is currently the Technical Director for Eurofins Specialty Services. He brings 20 years of experience in the environmental laboratory industry with a focus on HRGS/HRMS analyses and also LC-MS/MS analysis of PFAS. Prior to Eurofins, Andrew was the Technical Director for Vista Analytical Laboratory in Northern California where he developed all aspects of PFAS capability within the lab. Before time at Vista, Andrew worked in both the HRMS and LCMS laboratories at Alta Analytical with a focus on developing fringe EPA methods such as 1614, 1699, and 1694. Andrew holds a Bachelor’s of Science in Microbiology/Biochemistry from Cal Poly San Luis Obispo.