Empower Tips: Ask Me Anything About Calculating Signal to Noise Ratio

The calculation of signal to noise ratio is a critical parameter during method development, method validation and routine monitoring the performance of a chromatographic method. Both Limit of Detection (LOD or LDL) and Limit of Quantitation (LOQ or LQL) are based on signal to noise ratio. Empower can calculate signal to noise ratio in many ways. While we designed this functionality in Empower to comply with pharmacopeia requirements, there are alternative methods for this calculation.

Key points of discussion will be:

• Calculating Signal to Noise ratio as per USP/EP/JP Requirements
• Calculating Signal to Noise ratio using other options within the System Suitability option
• Calculating Signal to Noise ratio without the System Suitability Option

Please join us for a live discussion. As always, don’t forget to bring your Empower questions for this exclusive opportunity to ask our experts anything about Empower Software.

Presenter: Neil Lander (Principal Product Manager, Waters Corporation)

Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager focusing on Informatics solutions. He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.