Simplify Volatiles Analysis. Part 4: Chromatographically Challenging Analyses

Direct mass spectrometry (DMS) facilitates faster method development and validation, plus provides high throughput for routine analysis. But the adoption of selected ion flow tube mass spectrometry (SIFT-MS) has additional benefit – simplification of analyses that are overly complicated using chromatographic methods.

This webinar will describe how analysis of important chromatographically challenging volatiles, such as formaldehyde, volatile fatty acids, organosulfur compounds (and hydrogen sulfide) and amines (and ammonia) is greatly simplified. Straightforward analysis without requiring derivatization, drying steps, or selection of special columns, detectors and/or analysis conditions is a direct result of the ultra-soft chemical ionization used in SIFT-MS.

This final webinar (of a series of four) on routine SIFT-MS analysis focuses particularly on formaldehyde, which is important across a wide range of industries (from environmental to pharmaceutical testing). One case study illustrates validation of an unconventional analytical method for regulatory submission.

Key Learning Objectives:

• Very brief review of SIFT-MS and its automation
• Why some volatiles are a real challenge for conventional lab methods
• Case studies illustrating how SIFT-MS simplifies analysis of chromatically challenging volatiles, such as formaldehyde, volatile fatty acids, hydrogen sulfide and organosulfur compounds, ammonia and amines, nitrosamines, and siloxanes
• How direct MS eliminates wasted time when targeting very volatile compounds

Who should attend:

• Laboratory managers and analysts in routine industrial and contract testing and research laboratories, particularly those working with the analysis of volatiles
• Laboratory managers and analysts in pharmaceutical, biomedical, industrial, consumer product, and environmental laboratories

Presenter: Mark Perkins, Ph.D. (Senior Applications Chemist, Anatune Limited, United Kingdom)

Mark is a senior applications chemist at Anatune Limited and a global authority in automated SIFT-MS. Mark has extensive experience in both conventional chromatographic methods as well as SIFT-MS. Prior to joining Anatune, he spent 12 years as a senior analyst and chromatography section manager at the Malaysian Rubber Board’s UK research center.

Presenter: Vaughan Langford, Ph.D. (Principal Scientist, Syft Technologies, New Zealand)

Vaughan joined Syft in 2002 after completing his PhD in Physical Chemistry at the University of Canterbury, and post-doctoral fellowships at the Universities of Geneva, Western Australia, and Canterbury. With an extensive background in diverse applications of SIFT-MS, he provides advanced applications training and support to SIFT-MS users globally.

Moderator: Cameron Smith (Editorial Team, SelectScience)

Cameron studied Biomedical Science at the University of the West of England, UK, specializing in medical microbiology and oncology during his final year. As a member of the Editorial team, he now plays an integral role in shaping the content on SelectScience.