ISCC 2016: Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap based GC-MS
Postery | 2016 | Thermo Fischer ScientificInstrumentace
GC/MSD, GC/MS/MS, GC/HRMS, GC/Orbitrap
ZaměřeníFarmaceutická analýza
VýrobceThermo Fischer Scientific
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Confident Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap-Mass-Spectrometer-Based GC-MS
2016|Thermo Fischer Scientific|Aplikace
Dominic Roberts,1 Andrew Feilden,2 Richard Barlow,2 Kyle D’Silva,1 and Paul Silcock11Thermo Fisher Scientific, Runcorn, UK2Smithers Rapra, Shawbury, UKKey WordsExtractables and Leachables, Q Exactive GC, Orbitrapmass spectrometry, differential analysis, unknownidentification, container closure system, pharmaceutical.IntroductionThe investigation of potentially toxic chemical impuritiesleaching from...
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Non-targeted screening of extractables from vial septa using high-resolution Orbitrap GC-MS
2021|Thermo Fischer Scientific|Aplikace
APPLICATION NOTE000206Non-targeted screening of extractables fromvial septa using high-resolution Orbitrap GC-MSAuthors: Jane Cooper, Cristian Cojocariu,and Dominic RobertsThermo Fisher Scientific,Hemel Hempstead, UKKeywords: High-resolution accurate mass,HRAM, gas chromatography, accuratemass, GC, Orbitrap Exploris GC, chemicalcomponents, extractables, septa, flameionization detection, FIDGoalThe aim of this...
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ASMS 2016: Identification of Leachable Impurities from Pharmaceutical Container Closure Materials Using Orbitrap based GC-MS
2016|Thermo Fischer Scientific|Postery
Dominic Roberts1, Andrew Feilden2, Richard Barlow2, Jason Cole1,Alexander Semyonov1, Kyle D’Silva1, and Paul Silcock11Thermo Fisher Scientific, Runcorn, UK; 2Smithers Rapra, Shawbury, UK.Poster Note 64741Identification of Leachable Impurities fromPharmaceutical Container Closure MaterialsUsing Orbitrap based GC-MSIdentificationofofLeachableLeachableImpuritiesImpuritiesfromfromPharmaPharmIdentification1 and1,1Andrew2,2Richard2,2Jason1,1Alexander1,1Kyle1 andDominicRobertsRoberts, AndrewFeildenFeilden, RichardBarlowBarlow, JasonColeCole, AlexanderSemyonovSemyonov,...
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AAPS: Analytical Workflow for Extractable and Leachable Impurities
2015|Thermo Fischer Scientific|Prezentace
Analytical Workflow for Extractable andLeachable ImpuritiesAAPS 2015 | 26 October 2015, Orlando FLKyle D’SilvaThe world leader in serving science WHAT areEXTRACTABLES and LEACHABLES?2 What is E&L testing for?3 Areas of concern4CONTAMINANTTOXICITYDRUGEFFICACYIs there risk of harmto the patient?Is there impact ondrug potency? Extractables & Leachables•...
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