Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Plasma Samples from Lean, Fat, and Obese Rats

Aplikace | 2011 | LECOInstrumentace
GCxGC, GC/MSD, GC/TOF
Zaměření
Metabolomika, Klinická analýza
Výrobce
Agilent Technologies, LECO
Klíčová slova
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Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat PlasmaJohn Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USAOBJECTIVESDemonstrate the enhanced detection and increased peak capacity available with...
Klíčová slova
pooled, pooledobese, obeselean, leanfat, fatgcxgc, gcxgcreplib, replibtofms, tofmsuniquemass, uniquemasspool, poolname, namepools, poolsburied, buriedsimilarity, similarityresolves, resolvesglucopyranose
Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat PlasmaJohn Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USAOBJECTIVESDemonstrate the enhanced detection and increased peak capacity available with...
Klíčová slova
pooled, pooledobese, obeselean, leanfat, fatgcxgc, gcxgcreplib, replibtofms, tofmsuniquemass, uniquemasspool, poolname, namepools, poolsburied, buriedsimilarity, similarityresolves, resolvesglucopyranose
GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury StudyJohn Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USAINTRODUCTIONMETHODSComprehensive two-dimensional gas chromatography time-of-flight massspectrometry has gained recognition as a principal...
Klíčová slova
gcxgc, gcxgctofms, tofmstraumatic, traumaticbrain, braincomprehensive, comprehensivemouse, mousevolatile, volatiledimensional, dimensionalflight, flightinjury, injurydifferentiate, differentiateillustrates, illustratesheptatms, heptatmsosphate, osphatetatms
Evaluation of Metabolite Variation by a Pooled Sample Approach between Normal Control and Traumatic Brain Injury MiceUsing GCxGC-TOFMS with Data Analysis Using a Software Driven Reference FeatureJohn Heim, Joe Binkley, and Liz Humston-Fulmer | LECO Corporation, Saint Joseph, MI USAINTRODUCTIONGCxGC–TOFMS...
Klíčová slova
pooled, pooledtraumatic, traumaticgcxgc, gcxgcmetabolite, metabolitebrain, braintofms, tofmsinjury, injurytbi, tbimainlib, mainlibnormal, normalcontrol, controlpools, poolsreference, referencectrl, ctrlvariations