Naše každoroční speciální akce na spotřební materiál* značky Agilent je opět tu! HAPPY WEEK proběhne od pondělí 13. 4. 2026 od 7:00 do pátku 17. 4. 2026 do 16:00.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Altium_Hppy_week_2026_0e2c89bc49.jpg" alt="Altium International: Happy Week 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Altium_Hppy_week_2026_0e2c89bc49.jpg 245w," sizes="100vw" width="940" height="475"><blockquote>📅 Omezená platnost: Cenové nabídky na produkty Agilent platné během tohoto týdne mají omezenou platnost uvedenou přímo v jejich hlavičce.💻 Jak získat slevu:&nbsp;Objednávky posílejte na e-mailovou adresu objednavky.cz@altium.net, nezapomeňte na promo kód HPAT0426.</blockquote>Jste registrovaní v našem e‑shopu? Pak po zadání promo kódu HPAT0426 v košíku získáte výjimečnou slevu. Promo kód bude aktivní po celou dobu trvání akce – od 13. 4. do 17. 4. do 16:00.* Upozornění: Sleva se nevztahuje na roční objednávky, ekonomická balení vialek, víček a stříkačkových filtrů, reagencie pro molekulární biologii, produkt Prozyme, servisní díly a kolony na zakázku. Slevu nelze kombinovat s jinými akcemi a slevami (např. s poinstalační slevou).

Altium Happy Week - 35% sleva na produkty spotřebního materiálu Agilent

<div><div>Náš imunitní systém je neuvěřitelně silný. Dokáže totiž mimo jiné sám rozpoznat a zničit rakovinné buňky. Nádorové buňky jsou ale na tento útok připravené: vytvářejí si vlastní „neviditelné štíty“, které je před imunitním systémem chrání.</div></div><div>Průlom v léčbě rakoviny přinesly látky, které dokážou imunitní buňky znovu aktivovat. Ty pak mohou proniknout neviditelným štítem nádoru a znovu proti němu zasáhnout. Bohužel je ale tato léčba účinná zatím jen u 20–50 % pacientů. Vědci a vědkyně proto hledají nové způsoby, jak imunitní buňky znovu aktivovat. Důležitou roli v tomto procesu hraje malá a dobře známá molekula zvaná adenosin.Když jsou nádorové buňky ve stresu nebo odumírají, uvolňují do svého okolí molekuly adenosintrifosfátu (ATP). Tím dávají imunitnímu systému najevo, že něco není v pořádku. Mikroprostředí nádoru však zároveň skrývá právě onen neviditelný štít, který uvolněné ATP rychle rozkládá na adenosin, a varovný signál tak zaniká. K této přeměně slouží dva enzymy označované CD39 a CD73.Uvolněný adenosin pak působí jako uklidňující chemický signál: váže se na imunitní buňky, zpomaluje je a snižuje jejich schopnost rozpoznávat a ničit rakovinné buňky. Pokud by se podařilo zablokovat enzym CD73, bylo by možné neviditelný štít nádoru vyřadit z provozu a otevřít tak novou cestu k léčbě rakoviny.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Nove_latky_mohou_podporit_imunitni_system_v_boji_s_rakovinou_88c5e82cd5.jpeg" alt="ÚOCHB: Nové látky mohou podpořit imunitní systém v boji s rakovinou" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Nove_latky_mohou_podporit_imunitni_system_v_boji_s_rakovinou_88c5e82cd5.jpeg 245w," sizes="100vw" width="661" height="363">Mezioborové týmy z ÚOCHB vedené Janem Řezáčem, Janem Konvalinkou a Michalem Hockem využily novou metodu vysokokapacitního screeningu a otestovaly více než 5000 sloučenin. Díky tomu objevily dva deriváty ribonukleosidů, které se ukázaly jako slibné inhibitory enzymu CD73.Vědci pak jejich účinnost dál zvýšili úpravami základní chemické struktury, zejména přidáním prostorově objemných (hetero)arylových skupin. Následná optimalizace navíc zlepšila i jejich farmakokinetické vlastnosti, tedy jak se léčivá látka v organismu vstřebává, distribuuje, metabolizuje a vylučuje. Výsledkem jsou sloučeniny, které vydrží v organismu dostatečně dlouhou dobu, zároveň mají vysokou rozpustnost a také selektivitu vůči příbuzným enzymům, například právě CD39.Buněčné experimenty ukázaly, že tyto látky snižují produkci adenosinu v rakovinných buňkách, obnovují aktivaci imunitních T buněk a zároveň nepůsobí toxicky na lidské tkáňové buňky. Nejúčinnější ze zkoumaných látek dosáhla inhibiční konstanty v řádu jednotek pikomolů. Jedná se o hodnotu, která vyjadřuje, jak silně se inhibitor váže na cílový enzym nebo receptor a jak účinně ho blokuje. Čím nižší je tato hodnota, tím silněji a účinněji inhibitor na svůj cíl působí.Publikované výsledky představují důležitý výchozí bod pro navazující výzkum a další rozvoj této slibné třídy látek. Budoucí studie in vivo i kombinované experimenty nyní pomohou podrobněji prověřit účinnost těchto látek a ukázat, do jaké míry by mohly najít uplatnění v léčbě nádorových onemocnění.<blockquote><h4>Původní článek</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsptsci.5c00707">Silné kompetitivní inhibitory ekto-5′-nukleotidázy (CD73) na bázi 6-(het)aryl-7-deazapurinových ribonukleosidových 5′-O-bisfosfonátů</a></h4>Ugnė Šinkevičiu̅tė, Magdalena Šímová, Radek Staník, Lenka Poštová Slavětínská, Kristýna Blažková, Pavel Šácha, Martin Lepšík, Jan Řezáč, Jan Konvalinka, Tereza Ormsby, Michal Tichý, Michal HocekACS Pharmacol. Transl. Sci. 2026, 9, 1, 191–213<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsptsci.5c00707">https://pubs.acs.org/doi/10.1021/acsptsci.5c00707</a><h6>licencováno pod <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstrakt</h4>CD73 produkuje v mikroprostředí nádoru imunosupresivní adenosin a představuje slibný cíl pro imunoterapii nádorových onemocnění. Navrhli jsme a systematicky studovali rozmanité 2-substituované 7-deazapurinové ribonukleosidové 5′-O-bisfosfonáty nesoucí různé (het)arylové skupiny v poloze 6 a prokázali jsme jejich vysoce účinnou a selektivní inhibiční aktivitu vůči CD73. Nejaktivnější sloučeniny (s Ki v řádu jednotek pikomolů) obsahovaly v poloze 6 bicyklické (het)arylové skupiny v kombinaci s chlorem v poloze 2. Další optimalizace farmakokinetických vlastností vedla k identifikaci inhibitorů s nízkou clearance, dlouhým poločasem, vysokou rozpustností a vynikající selektivitou vůči CD39 a NTPDase3. Tyto sloučeniny účinně potlačovaly tvorbu adenosinu v buňkách MDA-MB-231, obnovovaly aktivaci CD8+ T lymfocytů a byly netoxické vůči lidským fibroblastům. Celkově se jejich profil příznivě srovnává s AB680, inhibitorem CD73, který je v současnosti ve fázi I/II klinických studií.</div>

Nové látky mohou podpořit imunitní systém v boji s rakovinou

V týdnu od 13. dubna na Vás čekají v oblasti plynné/pevné fáze a především GC, GC/MS, Raman a FTIR následující webináře.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://www.gcms.cz/webinars">👉 DETAILY A REGISTRACE V SEKCI WEBINÁŘE</a></h4></blockquote><blockquote>👉 Vyhledávejte a filtrujte v největší globální databázi s více než 5 500 GC, HPLC, MS a spektroskopickými webináři.</blockquote><h5>1. Agilent Technologies: The Journey of Safer Science through Safer Labs</h5><ul><li>Út, 14.4.2026 07:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/webinar/6104">Registrace</a></li></ul>Webinář zaměřený na bezpečnostní postupy v laboratořích, řízení rizik EHS a moderní řešení pro bezpečnější a efektivnější provoz.<h5>2. Agilent Technologies: Column Confidence: Making the Right Choice for Your GC Needs</h5><ul><li>Út, 14.4.2026 17:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/webinar/5725">Registrace</a></li></ul>Naučte se vybrat správnou GC/GC-MS kolonu na základě stacionární fáze a rozměrů kapiláry pro optimalizaci selektivity a rozlišení.<h5>3. Metrohm: Measure smarter, spend less – NIR spectroscopy for polymer analysis</h5><ul><li>Čt, 16.4.2026 15:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/webinar/6032">Registrace</a></li></ul>Zjistěte, jak NIR spektroskopie umožňuje rychlou a nedestruktivní analýzu polymerů bez použití chemikálií.<h5>4. C&amp;EN: Precision Lab Solutions for High-End Optics and Coatings</h5><ul><li>Čt, 16.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/webinar/6096">Registrace</a></li></ul>Diskuse s odborníky o pokročilých analytických metodách a testování optických materiálů pomocí UV/Vis a IR technik.

Webináře LabRulezGCMS týden 16/2026

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Věda a výzkum

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Je autorizovaným distributorem společnosti Agilent Technologies pro Českou republiku v oblastech chromatografie (GC, HPLC, UHPLC, kapilární elektroforéza) a hmotnostní spektrometrie (GC/MS, LC/MS, CE/MS), disolučních aparátů, molekulární (UV-Vis, UV-Vis-NIR, fluorescence, FTIR analyzátory a mikroskopy) a atomové spektroskopie (ICP-OES, ICP-MS, AAS), a v neposlední řadě také v oblasti molekulární biologie a genomiky (analýza nukleových kyselin a proteinů, microarray skenery a skla, PCR & RT-PCR, qPCR, řešení pro NGS, reagencie pro mutagenezi a klonování, sondy FISH a další).

Altium International

ÚOCHB AV ČR je přední mezinárodně uznávaná vědecká instituce, jejímž hlavním posláním je základní výzkum v oblasti chemické biologie a medicinální chemie, organické a materiálové chemie, chemie přírodních látek, biochemie a molekulární biologie, fyzikální chemie, teoretické chemie a analytické chemie.

Ústav organické chemie a biochemie AV ČR

Vše ze světa analytické chemie na jednom místě. Propojujeme lidi při řešení jejich problémů. U nás naleznete všechny potřebné informace snadno, rychle a přehledně. Přestaňte hledat a začněte nacházet.

LabRulez

Metrohm

Agilent Technologies

Bruker

Restek Corporation

C&EN

Shimadzu Corporation

Waters Corporation

Join us on the hunt for the needle in the haystack!This session will delve into best practices for untargeted feature finding, focusing on achieving the optimal balance between sample coverage and processing speed using Profinder and the new MassHunter Explorer. We will explore techniques to differentiate between features and noise by applying the right filters for quality checking your data. Additionally, the webinar will cover essential aspects of compound identification, including database matching, formula generation, and structure elucidation.This is a must-attend event for anyone looking to enhance their analytical capabilities and streamline their data processing workflows.<blockquote>Presenter: &nbsp;Stefan Schaebler (Application Specialist LC/MS, Agilent Technologies)Stefan completed his PhD in Biology, specializing in LC-MS-based lipidomics and metabolomics. Following his doctoral studies, he joined Agilent Technologies as an LC/MS Application Specialist. In this role, Stefan focuses on small molecule applications using LC-QTOF, with a strong emphasis on software tools and data interpretation.</blockquote>

Agilent Technologies: MassHunter Masterclass Months

Finding the Needle in the Haystack Part I: From Complex Samples to Compounds of Interest

The best practices for untargeted feature finding, focusing on achieving the optimal balance between sample coverage and processing speed.

From Complex Samples to Compounds of Interest

<div><div><div>Conventional GC-HRMS using EI data alone for non-target studies suffers from ambiguous identification of unknowns in NIST library searches due to less specific fragmentation, missing molecular ion signals or compound absence in the reference library. Library searches become prone for false positive assignment. To increase compound identification certainty, the addition of the molecular information, e.g., via CI is mandatory.See how a novel GC-HRMS approach with simultaneous EI and CI data acquisition in a single GC run dramatically improves the quality of information and identification certainty. Non-target studies in wastewater analysis, human metabolites, vegan food similarity and material emission prove a game-changing power of the system.Why to join this webinar:<ul><li>Understand the power of simultaneous EI and CI-HRMS data in single GC runs</li><li>Learn how to get to a safe and confident identification of unknowns in suspect and non-target GC-MS</li><li>Get to know a novel CI source with unmatched performance due to a wide selection of reagent ions and “zero” instrument downtime&nbsp;</li><li>Accelerate your analysis and post-processing time plus optimize your instrument uptime with no need of hardware switching</li></ul><blockquote>Presenter: Arnd Ingendoh (VP Business Development Applied Markets, Bruker Daltonics GmbH &amp; Co KG)Arnd Ingendoh received his PhD in biophysics 1994 in the group of Franz Hillenkamp and Michael Karas who developed and invented MALDI. Following two years at ThermoFisher and Bruker in Japan and the USA as an application specialist, he moved through various management positions at Bruker Daltonics in Germany with +15 years of service as Senior Vice President for Commercial Operations EMEA.After 25 years at Bruker, he changed to a start-up company from New Zealand, Syft Technologies, to build the European commercial organization as the Vice President Europe for real-time mass spectrometry applications like air monitoring, food quality testing and monitoring of industrial processes. In 2023, he rejoined Bruker as the VP Business Development for the Applied Mass Spectrometry division. His goal is to develop and introduce novel and potentially disruptive technologies for the applied markets. Aside of his commercial activities, Arnd had active roles in academic education, e.g. as a Guest Professor at the University of Vienna. He is author or co-author of more than 60 publications.Presenter: Sonja Klee (Produkt Manager ecTOF, TOFWERK AG)Dr. Sonja Klee is Product Manager at TOFWERK, a leading mass spectrometer manufacturer based in Switzerland. Her journey in mass spectrometry began during her undergraduate studies in Chemistry at the University of Wuppertal, Germany, where she delved into ionization and mass spectrometry fundamentals in the group of Thorsten Benter. Both fundamental research and practical applications continued through her academic studies with her PhD in Physical Chemistry in 2014 on chemical ionization mechanisms in mass spectrometry for which she received the Wolfgang-Paul-Study Award of the German Society for Mass Spectrometry (DGMS). Following this, Dr. Klee was awarded a Postdoctoral Marie Curie Fellowship to contribute to the CLOUD TRAIN Network at CERN, Switzerland.Focus of this tenure was conducting complex experiments within the EU research program "CLOUD" utilizing various TOFWERK mass spectrometers. After her two-year postdoctoral position, she continued with TOFWERK, leveraging her expertise in ionization and mass spectrometry development in several key roles, including Leading Coordinator for Ion Source Technology and Project Manager. Dr. Klee's extensive research background and industrial experience have significantly contributed to the development and introduction of the ecTOF product line, a breakthrough solution for GC-MS based compound identification. Recognized for her expertise and leadership in the field, Dr. Klee was elected as an official board member of the Swiss Group for Mass Spectrometry (SGMS) in 2023. Here, she manages the "Education" portfolio, reflecting her commitment to advancing knowledge and innovation in mass spectrometry.</blockquote></div></div></div>

Bruker: Removing Barriers in Non-target GC/MS for the Confident Identification of Unknowns

Removing Barriers in Non-target GC/MS for the Confident Identification of Unknowns

Podívejte se, jak nový přístup GC-HRMS se současným sběrem dat EI a CI v jediném GC cyklu výrazně zlepšuje kvalitu informací a jistotu identifikace.

Non-target GC/MS for the Identification of Unknowns

Advanced manufacturing technologies (AMTs) can speed drug development, improve quality and minimize drug shortages. Consequently, the FDA encourages early adoption of these technologies.This webinar will explore how digital transformation enhances the efficiency, accuracy, and reliability of process analytical technology (PAT) and quality control systems. We will present the principles and applications of PAT highlighting the importance of real-time monitoring and high-fidelity control of production processes. Attendees will gain insights into the latest digital tools in quality assurance and process control, ensuring compliance with regulatory standards and improving overall product quality. They will learn how PAT and associated technologies improve knowledge transfer and propagate accessibility from R&amp;D to full-scale production. Join us to discover how these advances are shaping the future of late development and advanced manufacturing and learn practical strategies for implementing these technologies in your operations.Session 1: 11:00 a.m. Enabling Digitalization from R&amp;D to Manufacturing - AI Ready Data through Ingestion &amp; Standardization &nbsp;Session 2: 11:25 a.m. How vibrational spectroscopy helps to accelerate new drug development and troubleshoot drug productionSession 3: 11:50 a.m. The Benefits of Raman Spectroscopy for the Understanding and Control of Pharmaceutical ProcessesSession 4: 12:15 p.m. Advancing Continuous Process Monitoring and Optimization with Benchtop NMR in PATKey Learning Objectives:<ul><li>Become familiar with available PAT spectroscopic tools such as NMR, NIR, mid-IR and Raman as well as their key applications that can enhance process control and quality control goals.</li><li>How to deploy spectroscopic and digital tools in a way that will advance PAT objectives.</li><li>Gain awareness about the way that many companies have already made use of PAT strategies that have proven to be beneficial.</li></ul>Who Should Attend:<ul><li>Laboratory managers</li><li>Chromatographers</li><li>New product developers</li></ul><blockquote>Presenter: Sergey Shilov, PhD (NA Product Manager, Science, Bruker Optics)Presenter: Anna Codina PhD (Director, Pharmaceutical Business, Bruker BioSpin)Presenter: Mark Kemper (Associate Director, Business Development, Tornado Spectral Systems)Presenter: Matteo Pennestri, PhD (Product Manager, PAT &amp; Automation, Bruker Pharma)Presenter: Kelly McSweeney (Contributing Editor, C&amp;EN Media Group)</blockquote>&nbsp;

C&EN: The Latest on Digitalization, Process Analytical Technology and Quality Control

The Latest on Digitalization, Process Analytical Technology and Quality Control

Explore how digital transformation enhances the efficiency, accuracy, and reliability of process analytical technology (PAT) and quality control systems.

Digitalization, PAT and QC

Consumer products are complex mixtures that rely on careful formulations and precision chemistry to deliver the desired properties. These properties can be chemical (such as the peroxide content of an oxidizer), physical (such as polymer viscosity) or fungible (such as the reserve acidity of a mixture). Measuring these and other types of properties typically requires a fleet of instrumentation and is often limited to raw material input and final product testing. These testing throughput limits place a high burden on the analytical lab, making product improvement difficult. &nbsp;Near-infrared spectroscopy (NIR) is a laboratory tool that can relieve the throughput limitation and be deployed to multiple products and problems at the same time.&nbsp;Register for this webinar to hear Alex Mattingly, Product Specialist at Chemlink Laboratories, explain how he uses NIR to address manufacturing challenges and increase production efficiency. He will show how he implemented NIR and developed the analytical methods to replace complex wet-chemical assays. Lenzi Williams, Spectroscopy Product Specialist, will give an overview of NIR spectroscopy, including&nbsp;features of the new OMNIS NIR, and explain how the fundamentals of this technique make it well-suited for formulated products.Join these experts after the presentation and get your specific questions answered during the live Q&amp;A.<blockquote>Presenter: Alex Mattingly (Product Specialist, Chemlink)</blockquote><div><blockquote>Alex Mattingly is a Product Specialist at Chemlink and a graduate of Kennesaw State University’s chemistry program. Since joining the team at Chemlink, he has focused on developing spectrometric techniques for determining a variety of chemical characteristics in raw materials and finished goods. His quantitative models for peroxide analysis, using near-infrared spectroscopy have enabled a new level of productivity and efficiency in the lab.Presenter:&nbsp;Lenzi Williams (Spectroscopy Product Specialist, Metrohm USA)</blockquote><div><blockquote>Lenzi Williams is the Spectroscopy Product Specialist at Metrohm USA in Riverview, Florida. She received her Ph.D. in Physical Chemistry from Florida State University in Tallahassee, FL where her thesis focused on quantifying excited state dynamics of unique nanomaterials using ultrafast pump-probe spectroscopy and Raman spectroscopy. Lenzi joined Metrohm USA in February 2024, focusing on Raman and NIR Spectroscopy.</blockquote></div></div>

Metrohm: Slashing Inefficiencies in Consumer Product Manufacturing with NIR Spectroscopy

Slashing Inefficiencies in Consumer Product Manufacturing with NIR Spectroscopy

An overview of NIR spectroscopy, including features of the new OMNIS NIR.

Consumer Product Manufacturing with NIR Spectroscopy

This presentation will cover method development strategies and considerations for Solid-Phase Microextraction (SPME).Aspects of method development to be covered will span across SPME coating selection, as well as critical sampling parameters.Overcoming the challenges of developing quantitative SPME methods will be shown through examples of applications within the food and environmental areas.The discussion will further explore how SPME can enhance both the efficiency and robustness of sample preparation workflows.

RESTEK: Optimizing Solid-Phase Microextraction (SPME): Strategies for Robust and Efficient Sample Preparation

Optimizing Solid-Phase Microextraction (SPME): Strategies for Robust and Efficient Sample Preparation

This presentation will cover method development strategies and considerations for Solid-Phase Microextraction (SPME).

Optimizing Solid-Phase Microextraction (SPME)

Data helps power the analytical laboratory. However, converting vast amounts of data into actionable decisions and confidence in business critical operations is extremely challenging.Existing solutions require custom system integrations that are expensive and difficult to maintain. Join us as we launch our newest cloud software solution, waters_connect Data Intelligence, specifically developed to help overcome these challenges by proving near-real time, in depth dashboards and powerful purpose-built analytics on your Empower&nbsp;Software data, helping you to:<ul><li>Improve productivity</li><li>Reduce risk</li><li>Save money</li><li>Accelerate time-to-market</li></ul>Be confidently audit ready, access deeper insights, and improve your laboratory operations.<blockquote>Presenter: Jonathan Scott (Director of Product Management, Connected Science, Waters Corporation)Prior to joining Waters in 2012, Jonathan worked in the regulated bioanalytical space focusing on developing and validating small and large molecule LC-MS methods. While at Waters, Jonathan has held multiple roles within product management including a focus on mass detection and biopharmaceutical software.Presenter:&nbsp;Ben Dearnaley (Principal Product Owner, Connected Science, Waters Corporation)Ben has worked at Waters for 17 years, and 14 years in Pharma prior to that. His area of interest as both a customer and at Waters has been on how to leverage Empower meta-data into analytics and business intelligence which helps Empower stakeholders understand better how their laboratories are working, such as understanding system and resource utilization, laboratory workflows and potential data integrity issues. Ben was a key individual involved with EDS365 and is now working as a Cloud Product Owner with a focus on bringing Empower analytics into the Cloud.</blockquote>

Waters: Level-up your Empower data with in-depth dashboards and powerful custom data analytics

Level-up your Empower data with in-depth dashboards and powerful custom data analytics

In-depth dashboards and powerful custom data analytics

Level-up your Empower

With the need for risk assessment and testing plans looming on the horizon, join us to learn about the challenges of low-level nitrosamine detection for both LCMS and GCMS applications.We will explore the pressing questions of coming regulation, including guidance on NDSRIs, the differing use cases of the 4 Procedures of USP &lt;1469&gt; and how Shimadzu can be your partner in creating solutions to meet these requirements.As you prepare for the August 1, 2025 deadline, whether your needs will be nitrosamine discovery with LCMS-QTOF or high-sensitivity QC monitoring with headspace GC-MS/MS, Shimadzu has the hardware and applications to help you succeed.We will host a Q&amp;A session after the presentation to address any questions or comments.<blockquote>Presenter: Brian Domanski (Strategic Collaboration Scientist, Shimadzu Scientific Instruments)Brian has over 10 years working to provide LC and SFC solutions for Pharma, as well as experience with a wide range of chromatography techniques including RP, NP, HILIC, IEX, SEC/GPC, and IC. His focus also includes scalable Informatics and Data Integrity solutions.</blockquote>

Shimadzu: Are you Nitrosamine Ready? Solutions for Nitrosamine Analysis

Are you Nitrosamine Ready? Solutions for Nitrosamine Analysis

Join us to learn about the challenges of low-level nitrosamine detection for both LCMS and GCMS applications.

Solutions for Nitrosamine Analysis by LCMS and GCMS

The separation of compounds with very high vapor pressure (e.g., permanent gases, light hydrocarbons, volatiles) can either be performed on polysiloxane liquid phases under cryogenic conditions or with PLOT columns.Porous Layer Open Tubular (PLOT) columns offer a more convenient alternative, mainly because they can be operated at ambient GC oven conditions.PLOT columns are based on porous particles that are fixated to the inner wall of the capillary tubing and compounds are separated based on their difference in surface interactions with the solid stationary phase.In this webinar we will cover the principles of PLOT column separations and discuss an array of applications including permanent gases, light hydrocarbon isomers, sulfur compounds and oxygenates on Agilent’s comprehensive portfolio of PLOT columns.<blockquote>Presenter: Mark Sinnott (Application Engineer, Agilent Technologies, Inc.)Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Twin Falls Idaho.</blockquote>

Agilent Technologies: Becoming a Better Chromatographer - Educational Webinar Series

PLOT TWIST: Using PLOT Columns for the Analysis of Gasses and Very Volatile Compounds

We will cover the principles of PLOT column separations and discuss an array of applications including permanent gases, light hydrocarbon isomers...

Using PLOT Columns for the Analysis of Gasses

The complete Solution for Food Analysis: Presented by Retsch, CEM, Shimadzu and EltraAccurate and rapid food analysis is becoming increasingly important as regulations become stricter and consumers become more demanding. This expert day on food analysis will give you a comprehensive overview of the optimal steps from sample preparation to analysis, familiarize you with modern methods and bring you up to date.Registration is free of charge and without obligation.<div><h3>Reproducible sample preparation for food analysis&nbsp;</h3>Food occurs in different consistencies and is often inhomogeneous. For meaningful analysis, food laboratories require representative samples, which makes homogenization necessary as part of sample preparation.Ideally, this step should involve as little work as possible. The prepared subsample must represent both the laboratory sample and the initial sample. This would not be the case with an inhomogeneous sample, as some components of the initial sample could be over- or under-represented.</div><h5>In this webinar you will learn more about:</h5><ul><li>Homogenization, standard deviation, correct analysis values</li><li>How do I find the optimal method for my sample</li><li>Cryogenic grinding (dry ice, liquid nitrogen)</li><li>Suitable laboratory mills for homogenizing foodstuffs</li><li>Live demos of selected mills</li><li>Application examples</li><li>Grain size determination using sieve analysis</li></ul><blockquote>Presenter: Dr. Tanja Butt, Dr. Lena Weigold and Dr. Gerhard Beckers</blockquote>This webinar is part of a series of four webinars (Retsch, CEM, Shimadzu, Eltra). Please register for the time slot of each company which fits best. Americas should select the second time slot, Asia the first. Each presentation by the different companies requires an own registration. Here you can select the time slot for Retsch. For the other companies you need to visit the landingpage.

Reproducible sample preparation for food analysis

For meaningful analysis, food laboratories require representative samples, which makes homogenization necessary as part of sample preparation.

The complete Solution for Food Analysis: Presented by Retsch, CEM, Shimadzu and EltraAccurate and rapid food analysis is becoming increasingly important as regulations become stricter and consumers become more demanding. This expert day on food analysis will give you a comprehensive overview of the optimal steps from sample preparation to analysis, familiarize you with modern methods and bring you up to date.Registration is free of charge and without obligation.<div><div><div><div><div><h3>Heavy metals and pesticides in highly processed&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</h3>In the third part of the webinar series the focus is on analytics. Each step of food processing presents a source of contamination, which is why highly processed foods (ultra-processed foods (UPF)) should be viewed critically.Heavy metals are analyzed using ICP-MS and pesticides using GCMS/MS and SFC-LCMS/MS. You have the opportunity to get in touch with device experts and discuss your questions.</div></div>In this webinar, you will learn more about:<ul><li>How to measure pesticides in difficult samples using LC-MS/MS and SFC-MS/MS</li><li>Determination of pesticides in food samples using GC-MS/MS with hydrogen as carrier gas</li><li>Challenges and solutions for heavy metal analysis</li><li>How much heavy metals are lurking in trend food products?</li></ul>Presenters: Uwe Oppermann, Stéphane Moreau, Waldemar Weber and Johannes Hesper</div></div></div>

Heavy metals and pesticides in highly processed

Heavy metals are analyzed using ICP-MS and pesticides using GCMS/MS and SFC-LCMS/MS. 

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