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Utilization of Comprehensive Two-Dimensional Gas Chromatography Combined with Time of Flight Mass Spectrometry (GCxGC-TOFMS) for Small Metabolite Identifications in Complex Biological Samples

 

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® Small Molecule Metabolite Identifications in Diabetic Versus Non-Diabetic Urine Sample Groups Using Comprehensive Two-Dimensional Gas Chromatography Combined with Time-of-Flight Mass Spectrometry (GCxGC-TOFMS) John Heim, LECO Corporation; Saint Joseph, Michigan USA Key Words: Fisher Ratio, Sample Groups, Diabetes, Metabolite Profile…
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diabetic, diabeticgcxgc, gcxgcmolecule, moleculetofms, tofmssmall, smallmetabolite, metaboliteprofile, profilegroups, groupsderivatized, derivatizeddisease, diseasefisher, fishermetabolomic, metabolomicchromatof, chromatofurine, urinedimensional
® Delivering the Right Results GCxGC-TOFMS Data Interpretation of Metabolic Biomarkers from Diabetic and Non-diabetic Urine Utilizing Fisher Ratios Prior to Multivariate Analysis John R. Heim, Scott Pugh, and Mark Libardoni • LECO Corporation, St. Joseph, Michigan OVERVIEW EXPERIMENTAL METHODS…
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diabetic, diabeticmainlib, mainlibstatistical, statisticaldiseased, diseasedmultivariate, multivariategcxgc, gcxgctofms, tofmsfisher, fishernon, nondata, datachromatof, chromatofurine, urinecompare, compareanalysis, analysisratio
GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury Study John Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USA INTRODUCTION METHODS Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry has…
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gcxgc, gcxgctofms, tofmstraumatic, traumaticbrain, braincomprehensive, comprehensivemouse, mousedimensional, dimensionalvolatile, volatileflight, flightinjury, injurydifferentiate, differentiateheptatms, heptatmsosphate, osphatetatms, tatmsillustrates
Evaluation of Metabolite Variation by a Pooled Sample Approach between Normal Control and Traumatic Brain Injury Mice Using GCxGC-TOFMS with Data Analysis Using a Software Driven Reference Feature John Heim, Joe Binkley, and Liz Humston-Fulmer | LECO Corporation, Saint Joseph,…
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pooled, pooledtraumatic, traumaticgcxgc, gcxgcmetabolite, metabolitebrain, braintofms, tofmsinjury, injurytbi, tbimainlib, mainlibnormal, normalcontrol, controlpools, poolsreference, referencectrl, ctrlvariations
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