Utilization of Comprehensive Two-Dimensional Gas Chromatography Combined with Time of Flight Mass Spectrometry (GCxGC-TOFMS) for Small Metabolite Identifications in Complex Biological Samples | LabRulez GCMS
 

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®Small Molecule Metabolite Identifications in Diabetic VersusNon-Diabetic Urine Sample Groups Using ComprehensiveTwo-Dimensional Gas Chromatography Combined withTime-of-Flight Mass Spectrometry (GCxGC-TOFMS)John Heim, LECO Corporation; Saint Joseph, Michigan USAKey Words: Fisher Ratio, Sample Groups, Diabetes, Metabolite ProfileComprehensive two-dimensional gas chromatography(GCxGC) expands the peak...
Klíčová slova
diabetic, diabeticgcxgc, gcxgcmolecule, moleculetofms, tofmssmall, smallmetabolite, metaboliteprofile, profilegroups, groupsderivatized, derivatizeddisease, diseasefisher, fishermetabolomic, metabolomicchromatof, chromatofdimensional, dimensionaldifferences
®Delivering the Right ResultsGCxGC-TOFMS Data Interpretation of Metabolic Biomarkers from Diabetic andNon-diabetic Urine Utilizing Fisher Ratios Prior to Multivariate AnalysisJohn R. Heim, Scott Pugh, and Mark Libardoni • LECO Corporation, St. Joseph, MichiganOVERVIEWEXPERIMENTAL METHODS®Illustrate the application of the new features...
Klíčová slova
diabetic, diabeticmainlib, mainlibstatistical, statisticaldiseased, diseasedmultivariate, multivariategcxgc, gcxgcfisher, fishertofms, tofmsnon, nondata, datachromatof, chromatofurine, urinecompare, compareanalysis, analysisratio
Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat PlasmaJohn Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USAOBJECTIVESDemonstrate the enhanced detection and increased peak capacity available with...
Klíčová slova
pooled, pooledobese, obeselean, leanfat, fatgcxgc, gcxgcreplib, replibuniquemass, uniquemasspool, pooltofms, tofmsname, namepools, poolsburied, buriedsimilarity, similarityresolves, resolvesglucopyranose
GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury StudyJohn Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USAINTRODUCTIONMETHODSComprehensive two-dimensional gas chromatography time-of-flight massspectrometry has gained recognition as a principal...
Klíčová slova
gcxgc, gcxgctraumatic, traumatictofms, tofmsbrain, braincomprehensive, comprehensivemouse, mousedimensional, dimensionalflight, flightvolatile, volatileinjury, injurydifferentiate, differentiateheptatms, heptatmsosphate, osphatetatms, tatmsillustrates
 

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®Small Molecule Metabolite Identifications in Diabetic VersusNon-Diabetic Urine Sample Groups Using ComprehensiveTwo-Dimensional Gas Chromatography Combined withTime-of-Flight Mass Spectrometry (GCxGC-TOFMS)John Heim, LECO Corporation; Saint Joseph, Michigan USAKey Words: Fisher Ratio, Sample Groups, Diabetes, Metabolite ProfileComprehensive two-dimensional gas chromatography(GCxGC) expands the peak...
Klíčová slova
diabetic, diabeticgcxgc, gcxgcmolecule, moleculetofms, tofmssmall, smallmetabolite, metaboliteprofile, profilegroups, groupsderivatized, derivatizeddisease, diseasefisher, fishermetabolomic, metabolomicchromatof, chromatofdimensional, dimensionaldifferences
®Delivering the Right ResultsGCxGC-TOFMS Data Interpretation of Metabolic Biomarkers from Diabetic andNon-diabetic Urine Utilizing Fisher Ratios Prior to Multivariate AnalysisJohn R. Heim, Scott Pugh, and Mark Libardoni • LECO Corporation, St. Joseph, MichiganOVERVIEWEXPERIMENTAL METHODS®Illustrate the application of the new features...
Klíčová slova
diabetic, diabeticmainlib, mainlibstatistical, statisticaldiseased, diseasedmultivariate, multivariategcxgc, gcxgcfisher, fishertofms, tofmsnon, nondata, datachromatof, chromatofurine, urinecompare, compareanalysis, analysisratio
Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat PlasmaJohn Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USAOBJECTIVESDemonstrate the enhanced detection and increased peak capacity available with...
Klíčová slova
pooled, pooledobese, obeselean, leanfat, fatgcxgc, gcxgcreplib, replibuniquemass, uniquemasspool, pooltofms, tofmsname, namepools, poolsburied, buriedsimilarity, similarityresolves, resolvesglucopyranose
GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury StudyJohn Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USAINTRODUCTIONMETHODSComprehensive two-dimensional gas chromatography time-of-flight massspectrometry has gained recognition as a principal...
Klíčová slova
gcxgc, gcxgctraumatic, traumatictofms, tofmsbrain, braincomprehensive, comprehensivemouse, mousedimensional, dimensionalflight, flightvolatile, volatileinjury, injurydifferentiate, differentiateheptatms, heptatmsosphate, osphatetatms, tatmsillustrates
 

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